Tadalafil (Cialis) is a medication used to treat erectile dysfunction (ED). It is taken by mouth and works by increasing blood flow to the penis, which helps to cause an erection.
Guía de Salud Masculina
Tadalafil is a drug used to treat conditions such as erectile dysfunction (ED) in men, and 5 mg is a common dosage strength.
1. Mechanism of action
- Tadalafil inhibits the activity of phosphodiesterase 5 (PDE5) and reduces the degradation of cyclic guanosine (cGMP), thereby relaxing the smooth muscle in the corpus cavernosum and flowing blood into the penile tissue, promoting erection of the penis.
2. Application
1、Erectile dysfunction (ED)
- For many male patients with varying degrees of ED, 5 mg of tadalafil can be taken before sexual activity as needed or daily on a regular basis.
- When taken regularly, it can help improve the vascular endothelial function of the corpus cavernosum and improve the spontaneous recovery of erectile function.
2、Lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH)
- Tadalafil can also be used to improve LUTS caused by BPH in men. In this regard, a dose of 5 mg can relieve symptoms such as frequent urination, urgency, and incomplete urination to a certain extent.
3. Matters needing attention
1、adverse reactions
- Common adverse reactions include headache, facial flushing, indigestion, nasal congestion, back pain, myalgia, etc. These adverse reactions are mostly mild to moderate and usually resolve spontaneously after the effect of the drug disappears.
2、contraindications
- Tadalafil is strictly prohibited in patients who are taking any form of nitrates (such as nitroglycerin) because combination of the two may cause severe hypotension.
- People allergic to tadalafil should not use it.
3、Use in Specific Populations
- Elderly people: Generally no dose adjustment is needed, but they may be more sensitive to drugs and more prone to adverse reactions.
- Patients with liver and kidney dysfunction: Care should be taken when using, and the dose may need to be adjusted or use avoided. The specific decision should be made based on the degree of liver and kidney dysfunction damage.