Tadalafilo 5 mg: What You Need to Know
Guía de Salud Masculina
tadalafil 5 mg is a drug used to treat erectile dysfunction (ED) and lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). The following is a detailed description:
1. Pharmacological effects
1、Mechanisms for treating erectile dysfunction
- Tadalafil is a phosphodiesterase 5 (PDE5) inhibitor. During sexual stimulation, neurons in the corpus cavernosum release nitric oxide (NO). NO activates guanylate cyclase and increases cyclic guanosine phosphate (cGMP) levels, which leads to relaxation of the smooth muscle of the corpus cavernosum and blood flows into the corpus cavernosum, causing erection.
- While PDE5 degrades cGMP, tadalafil inhibits the activity of PDE5 and reduces the degradation of cGMP, allowing the smooth muscle of the corpus cavernosum to maintain a relaxed state under sexual stimulation, which helps improve erectile function.
2、Mechanism of treating lower urinary tract symptoms associated with benign prostatic hyperplasia
- PDE5 exists in the prostate and bladder neck. By inhibiting PDE5, tadalafil can relax prostate smooth muscle and bladder neck smooth muscle, and improve lower urinary tract symptoms in patients with benign prostatic hyperplasia, such as dysuria, frequent frequency, urgency, etc.
2. Usage and Dosage
1、erectile dysfunction
- For most patients, the recommended starting dose for on-demand tadalafil tablets is 10mg, taken before sexual intercourse, and the dose can be increased to 20mg or reduced to 5mg, depending on individual efficacy and tolerability.
- The maximum frequency of medication is once a day.
2、Lower urinary tract symptoms associated with benign prostatic hyperplasia
- The recommended dose is 5mg once daily, and the dose can be adjusted based on the patient's symptoms and tolerability.
3. Matters needing attention
1、cardiovascular disease
- Tadalafil has a mild vasodilator effect. The use of tadalafil is strictly prohibited in patients who are taking nitrates (such as nitroglycerin, isosorbide dinitrate, etc.) because the combination of the two may cause severe hypotension.
- Patients with a history of cardiovascular disease should assess cardiovascular function before using tadalafil and use it with caution.
2、other aspects
- It may cause adverse reactions such as headache, indigestion, back pain, and myalgia. If the adverse reactions are serious, you should seek medical advice promptly and adjust the treatment plan.
- Tadalafil is not indicated for women and children.
When using tadalafil 5mg, be sure to do it under the guidance of a doctor to ensure safety and effectiveness.